Products 2474876-09-8
CAS 2474876-09-8 appears in our catalog under these names: iBET–BD2, GSK046, GSK046, 99.70%, GSK046, 98%. Offered by: GLPBio, TargetMol, Biosynth, MedChemExpress, Ambeed. Available pack sizes: 10mg, 5mg, 10mM (in 1ml dmso), 100mg, 25mg, 50mg, 1mg, 5 mg.
GSK046 is a secondary carboxamide resulting from the formal condensation of the carboxy group of 4-acetamido-3-fluoro-5-[(1S)-1-phenylethoxy]benzoic acid with the amino group of trans-4-aminocyclohexanol. It is a potent pan-BD2 bromodomain inhibitor. It has a role as a bromodomain-containing protein 4 inhibitor and an antineoplastic agent. It is a secondary carboxamide, a member of acetamides, a member of benzamides, a member of benzenes, a member of cyclohexanols, an aromatic ether and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C23H27FN2O4 |
|---|---|
| Molecular weight | 414.5 g/mol |
| IUPAC name | 4-acetamido-3-fluoro-N-(4-hydroxycyclohexyl)-5-[(1S)-1-phenylethoxy]benzamide |
| InChIKey | FRBRZGLUFOZRGD-YCMKEVRSSA-N |
| SMILES | C[C@@H](C1=CC=CC=C1)OC2=C(C(=CC(=C2)C(=O)NC3CCC(CC3)O)F)NC(=O)C |
Computed by PubChem (NCBI)