Products 2654821-05-1
CAS 2654821-05-1 is the registry number for PROTAC EGFR degrader 12. Offered by: MedChemExpress. Available pack sizes: Get quote.
2-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-1-yl)-2-[5-[4-[2-[2-[1-[4-[[(3S)-2,6-dioxopiperidin-3-yl]amino]-2-fluorophenyl]-4-hydroxypiperidin-4-yl]acetyl]-2,6-diazaspiro[3.3]heptan-6-yl]phenyl]-7-fluoro-3-oxo-1H-isoindol-2-yl]-N-(1,3-thiazol-2-yl)acetamide (CAS 2654821-05-1) is a chemical compound with the molecular formula C48H48F2N10O6S and a molecular weight of 931.0 g/mol. IUPAC name: 2-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-1-yl)-2-[5-[4-[2-[2-[1-[4-[[(3S)-2,6-dioxopiperidin-3-yl]amino]-2-fluorophenyl]-4-hydroxypiperidin-4-yl]acetyl]-2,6-diazaspiro[3.3]heptan-6-yl]phenyl]-7-fluoro-3-oxo-1H-isoindol-2-yl]-N-(1,3-thiazol-2-yl)acetamide. InChIKey: GCMGHESATZAFCJ-VKPZIYMTSA-N.
| Molecular formula | C48H48F2N10O6S |
|---|---|
| Molecular weight | 931.0 g/mol |
| IUPAC name | 2-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-1-yl)-2-[5-[4-[2-[2-[1-[4-[[(3S)-2,6-dioxopiperidin-3-yl]amino]-2-fluorophenyl]-4-hydroxypiperidin-4-yl]acetyl]-2,6-diazaspiro[3.3]heptan-6-yl]phenyl]-7-fluoro-3-oxo-1H-isoindol-2-yl]-N-(1,3-thiazol-2-yl)acetamide |
| InChIKey | GCMGHESATZAFCJ-VKPZIYMTSA-N |
| SMILES | C1CC2=C(N=CN2C1)C(C(=O)NC3=NC=CS3)N4CC5=C(C4=O)C=C(C=C5F)C6=CC=C(C=C6)N7CC8(C7)CN(C8)C(=O)CC9(CCN(CC9)C1=C(C=C(C=C1)N[C@H]1CCC(=O)NC1=O)F)O |
Computed by PubChem (NCBI)
Synonyms:
orb3135492