Products 302-25-0

CAS 302-25-0 appears in our catalog under these names: Prednisolone phosphate, 11,17-dihydroxy-21-(phosphonooxy)-Pregna-1,4-diene-3,20-dione. Offered by: Chemat Brand, TRC. Available pack sizes: on request, 50mg.

Prednisolone phosphate
Chemat Brand
  • size: on request
  • Variants: 1
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11,17-dihydroxy-21-(phosphonooxy)-Pregna-1,4-diene-3,20-dione
TRC
  • size: 50mg
  • Variants: 1
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Structural formula: {0} (CAS {1})

Prednisolone phosphate is a synthetic glucocorticoid resulting from the formal condensation of the 21-hydroxy group of prednisolone with one of the hydroxy groups of phosphoric acid. It is a prodrug for prednisolone that is activated in vivo by phosphatases. It has a role as an antineoplastic agent, a prodrug, a glucocorticoid receptor agonist and an anti-inflammatory agent. It is a tertiary alpha-hydroxy ketone, a glucocorticoid, a 17alpha-hydroxy steroid, an 11beta-hydroxy steroid, a 20-oxo steroid, a steroid phosphate and a 3-oxo-Delta(1),Delta(4)-steroid. It is functionally related to a prednisolone. It is a conjugate acid of a prednisolone phosphate(2-).

Source: ChEBI

Identity
Molecular formulaC21H29O8P
Molecular weight440.4 g/mol
IUPAC name[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] dihydrogen phosphate
InChIKeyJDOZJEUDSLGTLU-VWUMJDOOSA-N
SMILESC[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)COP(=O)(O)O)O)CCC4=CC(=O)C=C[C@]34C)O

Computed by PubChem (NCBI)

Synonyms: Prednisolone phosphate, prednisolone 21-monophosphate, Prednisolone 21-(dihydrogen phosphate), 11beta,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl dihydrogen phosphate, Prednisolone Phosphoric Acid, 11,17-dihydroxy-21-(phosphonooxy)-Pregna-1,4-diene-3,20-dione, 11beta,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate), prednisolone-sodium-phosphate, PREDNISOLONE PHOSPHATE [WHO-DD]