Products 3043908-63-7
CAS 3043908-63-7 is the registry number for PROTAC pan-KRAS degrader-1. Offered by: MedChemExpress. Available pack sizes: Get quote.
(2S,4R)-1-[(2S)-2-[4-[5-[1-[[1-[[7-(8-ethyl-7-fluoro-3-hydroxynaphthalen-1-yl)-8-fluoro-4-[(3R)-3-hydroxy-3-methylpiperidin-1-yl]pyrido[4,3-d]pyrimidin-2-yl]oxymethyl]cyclopropyl]methyl]piperidin-4-yl]oxypyrazin-2-yl]triazol-1-yl]-3-methylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide (CAS 3043908-63-7) is a chemical compound with the molecular formula C63H71F2N13O7S and a molecular weight of 1192.4 g/mol. IUPAC name: (2S,4R)-1-[(2S)-2-[4-[5-[1-[[1-[[7-(8-ethyl-7-fluoro-3-hydroxynaphthalen-1-yl)-8-fluoro-4-[(3R)-3-hydroxy-3-methylpiperidin-1-yl]pyrido[4,3-d]pyrimidin-2-yl]oxymethyl]cyclopropyl]methyl]piperidin-4-yl]oxypyrazin-2-yl]triazol-1-yl]-3-methylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide. InChIKey: JELHLMJKGQYGFM-WIWIRLKUSA-N.
| Molecular formula | C63H71F2N13O7S |
|---|---|
| Molecular weight | 1192.4 g/mol |
| IUPAC name | (2S,4R)-1-[(2S)-2-[4-[5-[1-[[1-[[7-(8-ethyl-7-fluoro-3-hydroxynaphthalen-1-yl)-8-fluoro-4-[(3R)-3-hydroxy-3-methylpiperidin-1-yl]pyrido[4,3-d]pyrimidin-2-yl]oxymethyl]cyclopropyl]methyl]piperidin-4-yl]oxypyrazin-2-yl]triazol-1-yl]-3-methylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide |
| InChIKey | JELHLMJKGQYGFM-WIWIRLKUSA-N |
| SMILES | CCC1=C(C=CC2=CC(=CC(=C21)C3=NC=C4C(=C3F)N=C(N=C4N5CCC[C@@](C5)(C)O)OCC6(CC6)CN7CCC(CC7)OC8=NC=C(N=C8)C9=CN(N=N9)[C@@H](C(C)C)C(=O)N1C[C@@H](C[C@H]1C(=O)N[C@@H](C)C1=CC=C(C=C1)C1=C(N=CS1)C)O)O)F |
Computed by PubChem (NCBI)
Synonyms:
PROTAC pan-KRAS degrader-1, orb3135627