Products 307510-92-5

CAS 307510-92-5 appears in our catalog under these names: CFTR Inhibitor-172, CFTRinh–172, CFTR(inh)-172/ 99.94% (existing batch purity), CFTR(inh)-172 99%, CFTR(INH)-172. Offered by: TRC, GLPBio, TargetMol, Ambeed, Sigma-Aldrich. Available pack sizes: 100mg, 10mg, 10mM (in 1ml dmso), 50mg, 1mg, 2mg, 5mg, 25mg.

Structural formula: {0} (CAS {1})

CFTRinh-172 is a thiazolidinone that is 2-thioxo-4-thiazolidinone which is substituted at position 3 by a (m--trifluoromethyl)phenyl group and at position 5 by a p-carboxybenzylidene group. It is an inhibitor of cystic fibrosis transmembrane conductance regulator, a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene. It has a role as an EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor. It is a member of benzoic acids, a thiazolidinone and a member of (trifluoromethyl)benzenes.

Source: ChEBI

Identity
Molecular formulaC18H10F3NO3S2
Molecular weight409.4 g/mol
IUPAC name4-[[4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene]methyl]benzoic acid
InChIKeyJIMHYXZZCWVCMI-UHFFFAOYSA-N
SMILESC1=CC(=CC(=C1)N2C(=O)C(=CC3=CC=C(C=C3)C(=O)O)SC2=S)C(F)(F)F

Computed by PubChem (NCBI)