Products 332012-40-5
CAS 332012-40-5 appears in our catalog under these names: Telatinib (BAY 57–9352), Telatinib, Telatinib/ 98.95% (existing batch purity), Telatinib, 99%, 99%, Telatinib, 99.37%. Offered by: GLPBio, TRC, TargetMol, Biosynth, Chemat. Available pack sizes: 5mg, 100mg, 10mg, 10mM (in 1ml dmso), 50mg, 25mg, 25 mg, 50 mg.
Telatinib is a member of the class of furopyridazines that is furo[2,3-d]pyridazine substituted by (4-chlorophenyl)amino and [2-(methylcarbamoyl)pyridin-4-yl]methoxy groups at positions 4 and 7, respectively. It is a potent inhibitor of VEGFR2/3, c-Kit and PDGFRalpha. It has a role as an antineoplastic agent, an angiogenesis inhibitor, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor, a vascular endothelial growth factor receptor antagonist and an apoptosis inducer. It is a member of anilines, a furopyridazine, a pyridinecarboxamide, an aromatic ether and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C20H16ClN5O3 |
|---|---|
| Molecular weight | 409.8 g/mol |
| IUPAC name | 4-[[4-(4-chloroanilino)furo[2,3-d]pyridazin-7-yl]oxymethyl]-N-methylpyridine-2-carboxamide |
| InChIKey | QFCXANHHBCGMAS-UHFFFAOYSA-N |
| SMILES | CNC(=O)C1=NC=CC(=C1)COC2=NN=C(C3=C2OC=C3)NC4=CC=C(C=C4)Cl |
Computed by PubChem (NCBI)