Products 33320-16-0
CAS 33320-16-0 is the registry number for Methyl aminolevulinate. Offered by: Chemat Brand, TargetMol, Biosynth, MedChemExpress. Available pack sizes: on request, 25mg, 50mg, 100mg, 5g, Get quote.
Methyl 5-aminolevulinate is the methyl ester of 5-aminolevulinic acid. A prodrug, it is metabolised to protoporphyrin IX, a photosensitizer, and is used in the photodynamic treatment of non-melanoma skin cancer (including basal cell carcinoma). Topical application (often as the hydrochloride salt) results in an accumulation of protoporphyrin IX in the skin lesions to which the cream has been applied. Subsequent illumination with red light results in the generation of toxic singlet oxygen that destroys cell membranes and thereby kills the tumour cells. It has a role as an antineoplastic agent, a photosensitizing agent, a dermatologic drug and a prodrug. It is functionally related to a 5-aminolevulinic acid.
Source: ChEBI
| Molecular formula | C6H11NO3 |
|---|---|
| Molecular weight | 145.16 g/mol |
| IUPAC name | methyl 5-amino-4-oxopentanoate |
| InChIKey | YUUAYBAIHCDHHD-UHFFFAOYSA-N |
| SMILES | COC(=O)CCC(=O)CN |
Computed by PubChem (NCBI)