Products 342639-96-7
CAS 342639-96-7 appears in our catalog under these names: KRIBB11/ 98%, KRIBB11, KRIBB 11, Heat Shock Factor 1 Inhibito 1PC X 10MG, Heat Shock Factor 1 Inhibito 1PC X 500MG. Offered by: TargetMol, GLPBio, Biosynth, Sigma-Aldrich, MedChemExpress. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 200mg, 500mg, 10mM/1mL.
KRIBB11 is a member of the class of indazoles that is 1H-indazole substituted by a [6-(methylamino)-3-nitropyridin-2-yl]amino group at position 5. It is an inhibitor of heat shock factor 1 (IC50 = 1.2M) and suppresses tumour growth in mouse xenograft models. It has a role as a heat shock factor 1 inhibitor, an antineoplastic agent and an apoptosis inducer. It is an aromatic amine, a C-nitro compound, an aminopyridine and a member of indazoles.
Source: ChEBI
| Molecular formula | C13H12N6O2 |
|---|---|
| Molecular weight | 284.27 g/mol |
| IUPAC name | 2-N-(1H-indazol-5-yl)-6-N-methyl-3-nitropyridine-2,6-diamine |
| InChIKey | NDJJEQIMIJJCLL-UHFFFAOYSA-N |
| SMILES | CNC1=NC(=C(C=C1)[N+](=O)[O-])NC2=CC3=C(C=C2)NN=C3 |
Computed by PubChem (NCBI)
Synonyms:
N2-(1H-indazol-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine, 2-N-(1H-indazol-5-yl)-6-N-methyl-3-nitropyridine-2,6-diamine, N2-(1H-indazole-5-yl)-N6-methyl-3-nitropyridine-2,6-diamine, orb1225248, orb1303955, s8402, N2-(5-Indazolyl)-N6-methyl-3-nitropyridine-2,6-diamine, 2,6-Pyridinediamine, N2-1H-indazol-5-yl-N6-methyl-3-nitro-, N2-(1H-indazol-5-yl)-N6-methyl-3-nitro-pyridine-2,6-diamine, N(2)-(1H-indazol-5-yl)-N(6)-methyl-3-nitropyridine-2,6-diamine