Products 348086-66-8

CAS 348086-66-8 appears in our catalog under these names: Z-Leu-Leu-Glu-AMC, Z-LLE-AMC, Z–LLE–AMC, Z-Leu-Leu-Glu-AMC, 95.00%, Z-Leu-Leu-Glu-MCA. Offered by: Creative Peptides, TargetMol, GLPBio, Chemat, Biosynth. Available pack sizes: on request, 1mg, 5mg, 10mg, 25mg, 100mg, 50 mg, 10 mg.

Z-Leu-Leu-Glu-AMC
Creative Peptides, Biosynth
  • size: on request, 5mg, 10mg, 25mg
  • Variants: 4
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Z-LLE-AMC
TargetMol
  • size: 1mg, 5mg, 10mg
  • Variants: 3
from 890.92
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Z–LLE–AMC
GLPBio
  • size: 1mg, 10mg, 25mg, 5mg
  • Variants: 4
from 774.90
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Z-Leu-Leu-Glu-AMC, 95.00%
Chemat
  • size: 1mg, 5mg
  • Variants: 2
from 503.92
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Z-Leu-Leu-Glu-MCA
Biosynth
  • size: 5mg
  • Variants: 1
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Z-Leu-Leu-Glu-AMC 95%
Ambeed
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 4
from 565.06
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(5S,8S,11S)-5,8-Diisobutyl-11-((4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatetradecan-14-oic acid, 95%, 95%
Chemat
  • size: 100mg, 1mg, 5mg, 10mg
  • Variants: 4
from 674.00
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Z-Leu-Leu-Glu-AMC, 99.91%
MedChemExpress
  • size: 50 mg, 10 mg, 10mM/1mL, 5 mg
  • Variants: 6
from 361.49
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Proteasome Substrate II (Fluorogenic), 98%
Fluorochem
  • size: 1mg, 5mg
  • Variants: 2
from 1263.11
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Structural formula: {0} (CAS {1})

Z-Leu-Leu-Glu-AMC is a tripeptide that is L-leu-L-leu-L-Glu with a Cbz group at the N-terminal and a 7-amino-4-methylcoumarin group at the C-terminal. It is a fluorogenic substrate for measuring the peptidylglutamyl peptide-hydrolyzing activity of the 20S proteasome. It has a role as a fluorochrome. It is a member of coumarins and a tripeptide. It is functionally related to a Leu-Leu-Glu.

Source: ChEBI

Identity
Molecular formulaC35H44N4O9
Molecular weight664.7 g/mol
IUPAC name(4S)-4-[[(2S)-4-methyl-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]pentanoyl]amino]-5-[(4-methyl-2-oxochromen-7-yl)amino]-5-oxopentanoic acid
InChIKeyFOYHOBVZPWIGJM-KCHLEUMXSA-N
SMILESCC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCC3=CC=CC=C3

Computed by PubChem (NCBI)

Synonyms: Z-Leu-Leu-Glu-AMC, Z-LLE-AMC, Cbz-Leu-Leu-Glu-AMC, Proteasome Substrate II (Fluorogenic), Z-Leu-Leu-Glu-MCA, Z-Leu-Leu-Glu-7-Amino-4-Methylcoumarin, Z-Leu-Leu-Glu-AMC [Z-LLE-AMC], Z-L-Leu-L-Leu-L-Glu-AMC, orb1692903, Z-Leu-Leu-Glu-7-amido-4-methylcoumarin, >=95%, solid