Products 382-67-2
CAS 382-67-2 appears in our catalog under these names: Desoximetasone, Dexamethasone EP Impurity F, Dexamethasone Impurity 6（Dexamethasone EP Impurity F）, Desoxymetasone, >95% (HPLC), Desoxymetasone. Offered by: Chemat Brand, Hubei YoungXin, TRC, Dr. Ehrenstorfer, Mikromol. Available pack sizes: on request, 10mg, 25mg, 50mg, 100mg, 200mg, 1mg, 5mg.
Desoximetasone is dexamethasone in which the hydroxy group at the 17alpha position is substituted by hydrogen. A synthetic corticosteroid with glucocorticoid activity, it is used as an anti-inflammatory and anti-pruritic in the treatment of various skin disorders, including skin allergies and psoriasis. It has a role as an anti-inflammatory drug and an antipruritic drug. It is a primary alpha-hydroxy ketone, a glucocorticoid, a 21-hydroxy steroid, an 11beta-hydroxy steroid, a 20-oxo steroid, a fluorinated steroid and a 3-oxo-Delta(1),Delta(4)-steroid.
Source: ChEBI
| Molecular formula | C22H29FO4 |
|---|---|
| Molecular weight | 376.5 g/mol |
| IUPAC name | (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one |
| InChIKey | VWVSBHGCDBMOOT-IIEHVVJPSA-N |
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@H]1C(=O)CO)C)O)F)C |
Computed by PubChem (NCBI)
Synonyms:
desoximetasone, Topicort, Desoxymethasone, Desoximetasona, Desoximetasonum, Topicort LP, Desossimetasone, 9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone, (11beta,16alpha)-9-Fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9-Fluoro-11-beta,21-dihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione