Products 397864-44-7

CAS 397864-44-7 appears in our catalog under these names: Fluticasone Furoate, Fluticasone Furoate, >95% (HPLC), Fluticasone furoate/ 99.58% (existing batch purity), Fluticasone furoate, Fluticasone furoate, 98.99%. Offered by: Chemat Brand, TRC, Mikromol, TargetMol, GLPBio. Available pack sizes: on request, 25mg, 50mg, 5mg, 250mg, 10mg, 100mg, 200mg.

Structural formula: {0} (CAS {1})

Fluticasone furoate is a trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a 2-furoyl substituent at position 17. Used in combination with vilanterol trifenate for treatment of bronchospasm associated with chronic obstructive pulmonary disease. It has a role as an anti-asthmatic drug, a prodrug and an anti-allergic agent. It is an 11beta-hydroxy steroid, a steroid ester, a fluorinated steroid, a 2-furoate ester, a corticosteroid, a thioester and a 3-oxo-Delta(1),Delta(4)-steroid. It is functionally related to a fluticasone. It derives from a hydride of an androstane.

Source: ChEBI

Identity
Molecular formulaC27H29F3O6S
Molecular weight538.6 g/mol
IUPAC name[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate
InChIKeyXTULMSXFIHGYFS-VLSRWLAYSA-N
SMILESC[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)SCF)OC(=O)C5=CC=CO5)C)O)F)C)F

Computed by PubChem (NCBI)