Products 42471-28-3
CAS 42471-28-3 is the registry number for Nimustine. Offered by: MedChemExpress. Available pack sizes: Get quote.
Nimustine is an organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-amino-2-methylpyrimidin-5-ylmethyl] group. An antineoplastic agent especially effective against malignant brain tumors. It has a role as an alkylating agent and an antineoplastic agent. It is an organochlorine compound, an aminopyrimidine and a member of N-nitrosoureas. It is a conjugate base of a nimustine(1+).
Source: ChEBI
| Molecular formula | C9H13ClN6O2 |
|---|---|
| Molecular weight | 272.69 g/mol |
| IUPAC name | 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitrosourea |
| InChIKey | VFEDRRNHLBGPNN-UHFFFAOYSA-N |
| SMILES | CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O |
Computed by PubChem (NCBI)
Synonyms:
NIMUSTINE, Nimustina, Nimustinum, 1-(4-Amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea, 3-(4-Amino-2-methyl-5-pyrimidinyl)methyl-1-(2-chloroethyl)-1-nitrosourea, 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-1-(2-chloroethyl)-1-nitrosourea, Urea, N'-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(2-chloroethyl)-N-nitroso-, 1-((4-Amino-2-methylpyrimidin-5-yl)methyl)-3-(2-chloroethyl)-3-nitrosourea, N'-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(2-chloroethyl)-N-nitrosourea, Nimustin