Products 442633-00-3
CAS 442633-00-3 appears in our catalog under these names: Arp2/3 Complex Inhibitor I, CK-666, Arp2/3 Complex Inhibitor I, 1PC X 25MG, CK 666, CK 666, CK-666/ 99.33% (existing batch purity). Offered by: Biosynth, Sigma-Aldrich, TRC, GLPBio, TargetMol. Available pack sizes: 50mg, 100mg, 25MG, 500mg, 10mg, 5mg, 10mM (in 1ml dmso), 1mg.
CK-666 is a member of the class of indoles that is 2-methyltryptamine in which a hydrogen attached to the primary amino group has been replaced by a 2-fluorobenzoyl group. It is a cell-permeable inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex which works by binding to Arp2/3 complex, stabilising the inactive state of the complex and preventing its movement into the active conformation. It has a role as an actin polymerisation inhibitor. It is a member of benzamides, a member of indoles and an organofluorine compound.
Source: ChEBI
| Molecular formula | C18H17FN2O |
|---|---|
| Molecular weight | 296.3 g/mol |
| IUPAC name | 2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide |
| InChIKey | UXRKUKRXVWJFER-UHFFFAOYSA-N |
| SMILES | CC1=C(C2=CC=CC=C2N1)CCNC(=O)C3=CC=CC=C3F |
Computed by PubChem (NCBI)
Synonyms:
2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide, 2-Fluoro-N-(2-(2-methyl-1H-indol-3-yl)ethyl)benzamide, 3ukr, UXRKUKRXVWJFER-UHFFFAOYSA-N, Oprea1_850670, orb1309829, 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)-ethyl]-benzamide, s7690, Arp2/3 Complex Inhibitor I, CK-666, 2-Fluoro-N-[2-(2-methyl-3-indolyl)ethyl]benzamide