Products 444731-52-6

CAS 444731-52-6 appears in our catalog under these names: Pazopanib, Pazopanib, >95% (HPLC), Pazopanib/ 99.84% (existing batch purity), Pazopanib (GW–786034), Pazopanib, >98.0%(HPLC)(T). Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Biosynth. Available pack sizes: on request, 100mg, 10mg, 50mg, 25mg, 200mg, 500mg, 10mM (in 1ml dmso).

Pazopanib
Chemat Brand, Biosynth, Thermo Scientific (Acros)
  • size: on request, 0,5g, 0,25g, 1g
  • Variants: 8
from 1643.69
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Pazopanib, >95% (HPLC)
TRC
  • size: 100mg, 10mg, 50mg
  • Variants: 3
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Pazopanib/ 99.84% (existing batch purity)
TargetMol
  • size: 10mg, 25mg, 50mg, 100mg
  • Variants: 6
from 458.82
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Pazopanib (GW–786034)
GLPBio
  • size: 100mg, 25mg, 10mM (in 1ml dmso), 500mg
  • Variants: 4
from 583.00
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Pazopanib, >98.0%(HPLC)(T)
TCI
  • size: 200mg, 1g
  • Variants: 2
from 346.03
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Pazopanib - Bio-X â„¢
Biosynth
  • size: 10mg
  • Variants: 1
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Pazopanib, 98.00%
Chemat
  • size: 100mg, 1g, 250mg
  • Variants: 3
from 339.13
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Pazopanib 99%
Ambeed
  • size: 1mg, 50mg, 100mg, 250mg
  • Variants: 7
from 120.06
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5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide, 99%, 99%
Chemat
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 5
from 107.60
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Pazopanib, 99.91%
MedChemExpress
  • size: 25 mg, 50 mg, 10 mg, 500 mg
  • Variants: 8
from 263.96
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Pazopanib (Standard)
MedChemExpress
  • size: 100 mg, 25 mg, 50 mg, 10 mg
  • Variants: 5
from 575.11
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Structural formula: {0} (CAS {1})

Pazopanib is a pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor, an angiogenesis modulating agent and a vascular endothelial growth factor receptor antagonist. It is a sulfonamide, an aminopyrimidine and a member of indazoles. It is a conjugate base of a pazopanib(1+).

Source: ChEBI

Identity
Molecular formulaC21H23N7O2S
Molecular weight437.5 g/mol
IUPAC name5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide
InChIKeyCUIHSIWYWATEQL-UHFFFAOYSA-N
SMILESCC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N

Computed by PubChem (NCBI)

Synonyms: Pazopanib, pazopanibum, Votrient, Pazopanib [INN], Pazopanib [INN:BAN], Pazopanib?, Pazopanib (Standard), indazolylpyrimidine 13, Pazopanib (free base), Kinome_3790
Related forms of this compound
2-methyl-5-[[4-[[3-methyl-2-(trideuteriomethyl)indazol-6-yl]-(trideuteriomethyl)amino]pyrimidin-2-yl]amino]benzenesulfonamide C21H23N7O2S
Isomers (same molecular formula)
5-[[2-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-4-yl]amino]-2-methylbenzenesulfonamide C21H23N7O2S