Products 446-86-6
CAS 446-86-6 appears in our catalog under these names: Azathioprine, Azathioprine, >95% (HPLC), Azathioprine , Azathioprine - Bio-X â„¢, Azathioprine, >98.0%(HPLC)(T). Offered by: Chemat Brand, TRC, Mikromol, LoGiCal, Dr. Ehrenstorfer. Available pack sizes: on request, 1g, 500mg, 50mg, 250mg, 10mg, 100mg, 10mM (in 1ml dmso).
Azathioprine is a thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. It has a role as an antimetabolite, an antineoplastic agent, an immunosuppressive agent, a prodrug, a carcinogenic agent, a hepatotoxic agent and a DNA synthesis inhibitor. It is a member of imidazoles, a thiopurine, an aryl sulfide and a C-nitro compound.
Source: ChEBI
| Molecular formula | C9H7N7O2S |
|---|---|
| Molecular weight | 277.27 g/mol |
| IUPAC name | 6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine |
| InChIKey | LMEKQMALGUDUQG-UHFFFAOYSA-N |
| SMILES | CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-] |
Computed by PubChem (NCBI)
Synonyms:
azathioprine, Azothioprine, Azanin, Azathioprin, Azatioprin, Azamun, Azasan, Ccucol, Imurek, Muran