Products 470-42-8
CAS 470-42-8 appears in our catalog under these names: Marinobufagin, Marinobufogenin, Marinobufagenin, Marinobufagenin, 99%, 99%, Marinobufogenin, 99.0%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Chemat. Available pack sizes: 25mg, 1mg, 5mg, 500ug, 2mg, 10mg, 50mg, 5 mg.
Marinobufagenin is a cardiotonic steroid secreted by the toad Bufo rubescens and other related species such as Bufo marinus. An endogenous Na/K-ATPase inhibitor, it is a vasoconstrictor with effects similar to digitalis. It has a role as an epitope and an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor. It is an epoxy steroid and a steroid hormone. It is functionally related to a (5beta)-bufadienolide.
Source: ChEBI
| Molecular formula | C24H32O5 |
|---|---|
| Molecular weight | 400.5 g/mol |
| IUPAC name | 5-[(1R,2S,4R,6R,7R,10S,11R,14S,16S)-14,16-dihydroxy-7,11-dimethyl-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-6-yl]pyran-2-one |
| InChIKey | JMNQTHQLNRILMH-OBBGIPBRSA-N |
| SMILES | C[C@]12CC[C@@H](C[C@]1(CC[C@@H]3[C@@H]2CC[C@]4([C@]35[C@H](O5)C[C@@H]4C6=COC(=O)C=C6)C)O)O |
Computed by PubChem (NCBI)
Synonyms:
Marinobufagenin, Marinobufagin, Marinobufogenin, MARCINOBUFAGIN, (3beta,5beta,14alpha,15beta)-3,5-dihydroxy-14,15-epoxybufa-20,22-dienolide, 3beta,5-dihydroxy-5beta,15beta-14,15-epoxybufa-20,22-dienolide, orb1684427, Bufa-20,22-dienolide, 14,15-epoxy-3,5-dihydroxy-, (3.beta.,5.beta.,15.beta.)-, 3-beta,5-Dihydroxy-14,15-beta-epoxy-5-beta-bufa-20,22-dienolide, 3beta,5beta-dihydroxy14beta,15beta-epoxy-bufa-20,22-dienolide