Products 477600-75-2
CAS 477600-75-2 appears in our catalog under these names: Tofacitinib, min. 95 %, 250 mg, Tofacitinib, Tofacitinib/ 99.74% (existing batch purity), Tofacitinib (CP–690550,Tasocitinib), Tofacitinib, 98.00%. Offered by: Roth, Chemat Brand, TargetMol, GLPBio, Chemat. Available pack sizes: 250mg, on request, 5mg, 10mg, 25mg, 50mg, 100mg, 200mg.
Tofacitinib is a pyrrolopyrimidine that is pyrrolo[2,3-d]pyrimidine substituted at position 4 by an N-methyl,N-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino moiety. Used as its citrate salt to treat moderately to severely active rheumatoid arthritis. It has a role as an antirheumatic drug and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a nitrile, a pyrrolopyrimidine, a N-acylpiperidine and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C16H20N6O |
|---|---|
| Molecular weight | 312.37 g/mol |
| IUPAC name | 3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile |
| InChIKey | UJLAWZDWDVHWOW-YPMHNXCESA-N |
| SMILES | C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N |
Computed by PubChem (NCBI)