CAS 489-32-7 appears in our catalog under these names: Icariin, Icariin, >95% (HPLC), Icariin/ 98.49% (existing batch purity), Icariin, 98% , Icariin, >96.0%(HPLC). Offered by: Chemat Brand, TRC, GLPBio, TargetMol, Thermo Scientific (Alfa Aesar). Available pack sizes: on request, 100mg, 1g, 5g, 10mM (in 1ml dmso), 50mg, 200mg, 500mg.
Icariin is a member of the class of flavonols that is kaempferol which is substituted at position 8 by a 3-methylbut-2-en-1-yl group and in which the hydroxy groups at positions 3, 4', and 7 have been converted to the corresponding 6-deoxy-alpha-L-mannopyranoside, methyl ether, and beta-D-glucopyranoside, respectively. A phoshphodiesterase-5 inhibitor, it is obtained from several species of plants in the genus Epimedium and is thought to be the main active ingredient of the Chinese herbal medicine Herba Epimedii (yinyanghuo). It has a role as an antioxidant, a bone density conservation agent, an EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor and a phytoestrogen. It is a member of flavonols and a glycosyloxyflavone.
Source: ChEBI
| Molecular formula | C33H40O15 |
|---|---|
| Molecular weight | 676.7 g/mol |
| IUPAC name | 5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one |
| InChIKey | TZJALUIVHRYQQB-XLRXWWTNSA-N |
| SMILES | C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O |
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