Products 491833-29-5

CAS 491833-29-5 appears in our catalog under these names: Eliglustat, Eliglustat/ 99.71% (existing batch purity), Eliglustat 98%, N-[(1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]octanamide, 98%, 98%, Eliglustat, 99.75%. Offered by: GLPBio, TRC, Mikromol, TargetMol, Biosynth. Available pack sizes: 5mg, 250mg, 1mg, 2mg, 10mg, 25mg, 50mg, 100mg.

Eliglustat
GLPBio, TRC, Mikromol
  • size: 5mg, 250mg, 1mg, 10mg
  • Variants: 13
from 690.65
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Eliglustat/ 99.71% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 8
from 525.34
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Eliglustat 98%
Ambeed
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 8
from 292.50
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N-[(1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]octanamide, 98%, 98%
Chemat
  • size: 10mg, 25mg, 50mg, 100mg
  • Variants: 7
from 227.60
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Eliglustat, 99.75%
MedChemExpress
  • size: 25 mg, 5 mg, 1 mg, 50 mg
  • Variants: 7
from 435.79
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Eliglustat (Standard)
MedChemExpress
  • size: 10 mg, 50 mg, 5 mg, 100 mg
  • Variants: 5
from 1550.35
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N-[(1R,2R)-1-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-1-HYDROXY-3-PYRROLIDIN-1-YLPROPAN-2-YL]OCTANAMIDE, 98%
Fluorochem
  • size: 10mg, 25mg, 50mg
  • Variants: 3
from 482.14
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Structural formula: {0} (CAS {1})

Eliglustat is a carboxamide obtained by formal condensation of the carboxy group of octanoic acid with the primary amino group of (1R,2R)-2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(pyrrolidin-1-yl)propan-1-ol. A ceramide glucosyltransferase inhibitor used (as its tartrate salt) for treatment of Gaucher's disease. It has a role as an EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor. It is a secondary alcohol, a carboxamide, a N-alkylpyrrolidine and a benzodioxine. It is a conjugate base of an eliglustat(1+).

Source: ChEBI

Identity
Molecular formulaC23H36N2O4
Molecular weight404.5 g/mol
IUPAC nameN-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide
InChIKeyFJZZPCZKBUKGGU-AUSIDOKSSA-N
SMILESCCCCCCCC(=O)N[C@H](CN1CCCC1)[C@@H](C2=CC3=C(C=C2)OCCO3)O

Computed by PubChem (NCBI)

Synonyms: ELIGLUSTAT, Genz-99067, Genz 99067, Eliglustatum, Eliglustat free base, Eliglustat [USAN:INN], s7852, 491833-29-5 (free base), ELIGLUSTAT [MI], ELIGLUSTAT [INN]
Related forms of this compound
N-[(1S,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide C23H36N2O4
N-[(1R,2S)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide C23H36N2O4
N-[(1S,2S)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide C23H36N2O4
Isomers (same molecular formula)
2-[[(1S,3aS,3bS,5aR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,8,9,9b,10,11-tetradecahydroindeno[5,4-f]quinoline-1-carbonyl]amino]-2-methylpropanoic acid C23H36N2O4