CAS 51116-01-9 appears in our catalog under these names: 8-bromo-cGMP sodium salt, 8-Bromo-cGMP sodium/ 99.91% (existing batch purity), 8–Bromo–cGMP, sodium salt, 8-Bromoguanosine 3'',5''-cyclic monophosphate sodium salt, 99.00%, 8-BROMOGUANOSINE 3':5'-CYCLIC &. Offered by: TRC, TargetMol, GLPBio, Chemat, Sigma-Aldrich. Available pack sizes: 500mg, 5mg, 10mg, 25mg, 100mg, 10mM (in 1ml water), 50mg, 250mg.
Sodium 8-bromo-3',5'-cyclic GMP is an organic sodium salt having 8-bromoguanosine 3',5'-cyclic phosphate as the counterion. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro. It has a role as a muscle relaxant and a protein kinase G agonist. It contains an 8-bromo-3',5'-cyclic GMP(1-).
Source: ChEBI
| Molecular formula | C10H10BrN5NaO7P |
|---|---|
| Molecular weight | 446.08 g/mol |
| IUPAC name | sodium 9-[(4aR,6R,7R,7aS)-7-hydroxy-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-8-bromo-1H-purin-6-one |
| InChIKey | ZJRFCXHKYQVNFK-YEOHUATISA-M |
| SMILES | C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=C(C(=O)NC(=N4)N)N=C3Br)O)OP(=O)(O1)[O-].[Na+] |
Computed by PubChem (NCBI)