CAS 516-21-2 appears in our catalog under these names: Cycloguanil HCl, Cycloguanil, Cycloguanil 98+%, Cycloguanil, 98+%, 98+%. Offered by: Chemat Brand, TargetMol, Ambeed, Chemat, MedChemExpress. Available pack sizes: on request, 25mg, 50mg, 100mg, 250mg, 1g, Get quote.
Cycloguanil is a triazine in which a 1,6-dihydro-1,3,5-triazine ring is substituted at N-1 by a 4-chlorophenyl group, at C-2 and -4 by amino groups and at C-6 by gem-dimethyl groups. A dihydrofolate reductase inhibitor, it is a metabolite of the antimalarial drug proguanil. It has a role as an antiinfective agent, an antiparasitic agent, an antiprotozoal drug, an antimalarial, an EC 1.5.1.3 (dihydrofolate reductase) inhibitor and an antifolate.
Source: ChEBI
| Molecular formula | C11H14ClN5 |
|---|---|
| Molecular weight | 251.71 g/mol |
| IUPAC name | 1-(4-chlorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine |
| InChIKey | QMNFFXRFOJIOKZ-UHFFFAOYSA-N |
| SMILES | CC1(N=C(N=C(N1C2=CC=C(C=C2)Cl)N)N)C |
Computed by PubChem (NCBI)