Products 51627-14-6

CAS 51627-14-6 is the registry number for Cefatrizine. Offered by: TRC, GLPBio, MedChemExpress. Available pack sizes: 50mg, 25mg, 5mg, Get quote.

Cefatrizine
TRC, GLPBio, MedChemExpress
  • size: 50mg, 25mg, 5mg, Get quote
  • Variants: 4
from 657.89
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Structural formula: {0} (CAS {1})

Cefatrizine is a cephalosporin compound having (1H-1,2,3-triazol-4-ylsulfanyl)methyl and [(2R)-2-amino-2-(4-hydroxyphenyl)]acetamido side-groups. An antibacterial drug first prepared in the 1970s, it has more recently been found to be an inhibitor of eukaryotic elongation factor-2 kinase (eEF2K), which is known to regulate apoptosis, autophagy and ER stress in many types of human cancers. It has a role as an EC 2.7.11.20 (elongation factor 2 kinase) inhibitor and an antibacterial drug. It is an amino acid amide, a cephalosporin, a carboxylic acid, a member of phenols, a member of triazoles and a semisynthetic derivative.

Source: ChEBI

Identity
Molecular formulaC18H18N6O5S2
Molecular weight462.5 g/mol
IUPAC name(6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-(2H-triazol-4-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKeyUOCJDOLVGGIYIQ-PBFPGSCMSA-N
SMILESC1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)C(=O)O)CSC4=NNN=C4

Computed by PubChem (NCBI)

Synonyms: CEFATRIZINE, Cefatrizinum, Antibiotic BL-S 640, cefatrizina, Cefatrizine (USAN), CEFATRIZINE [USAN], Cefatrizino, Cephatriazine, Orosporina, Cefatrix
Isomers (same molecular formula)
(6R,7R)-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid C18H18N6O5S2
(6R,7R)-7-[(2-hydroxy-2-phenylacetyl)amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid C18H18N6O5S2
(6R,7R)-7-[[(2S)-2-hydroxy-2-phenylacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid C18H18N6O5S2