Products 521984-48-5

CAS 521984-48-5 appears in our catalog under these names: SIS3 HCl, 1,2,3,4-Tetrahydro-6,7-dimethoxy-2-((2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl)-1-oxo-2-propenyl)-isoquinoline Monohydrochloride, (E)-SIS3/ 98.83% (existing batch purity), SIS3, SIS 3 Hydrochloride, >98.0%(HPLC). Offered by: GLPBio, TRC, TargetMol, Biosynth, TCI. Available pack sizes: 5mg, 1mg, 2,5mg, 2mg, 10mg, 25mg, 50mg, 100mg.

SIS3 HCl
GLPBio
  • size: 5mg, 1g, 2mg, 25mg
  • Variants: 5
from 639.16
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1,2,3,4-Tetrahydro-6,7-dimethoxy-2-((2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl)-1-oxo-2-propenyl)-isoquinoline Monohydrochloride
TRC
  • size: 1mg, 2,5mg, 5mg
  • Variants: 3
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(E)-SIS3/ 98.83% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 8
from 425.84
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SIS3
Biosynth
  • size: 1mg, 5mg, 10mg, 50mg
  • Variants: 5
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SIS 3 Hydrochloride, >98.0%(HPLC)
TCI
  • size: 5mg, 25mg
  • Variants: 2
from 536.31
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SIS3 HCl 99%
Ambeed
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 7
from 259.12
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SIS3, 97%, 97%
Chemat
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 6
from 93.20
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SIS3, 99.62%
MedChemExpress
  • size: 5 mg, 25 mg, 10mM/1mL, 2 mg
  • Variants: 7
from 435.79
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SIS3 is a hydrochloride resulting from the reaction of SIS3 free base with 1 mol eq. of hydrogen chloride. It has a role as a Smad3 inhibitor. It contains a SIS3 free base(1+).

Source: ChEBI

Identity
Molecular formulaC28H28ClN3O3
Molecular weight490.0 g/mol
IUPAC name(E)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one;hydrochloride
InChIKeyCDKIEBFIMCSCBB-CALJPSDSSA-N
SMILESCN1C(=C(C2=C1N=CC=C2)/C=C/C(=O)N3CCC4=CC(=C(C=C4C3)OC)OC)C5=CC=CC=C5.Cl

Computed by PubChem (NCBI)

Synonyms: Sis3 HCl, C28H28ClN3O3, Caneritinib, Specific Inhibitor of Smad3, orb1224814, orb1303973