CAS 53-79-2 appears in our catalog under these names: Puromycin dihydrochloride, 95%, Puromycin, Puromycin (CL13900), Puromycin, 10 mg/ml in distilled water, sterile-filtered , Puromycin-D3. Offered by: Combi-blocks, TargetMol, GLPBio, Thermo Scientific (Alfa Aesar), Biosynth. Available pack sizes: 100mg, 250mg, 1mg, 5mg, 10mg, 5x1ml, 1ml, 50mg.
Puromycin is an aminonucleoside antibiotic, derived from the Streptomyces alboniger bacterium, that causes premature chain termination during translation taking place in the ribosome. It has a role as a nucleoside antibiotic, an antimicrobial agent, an antiinfective agent, an antineoplastic agent, a protein synthesis inhibitor, an EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor and an EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor. It is a conjugate base of a puromycin(1+).
Source: ChEBI
| Molecular formula | C22H29N7O5 |
|---|---|
| Molecular weight | 471.5 g/mol |
| IUPAC name | (2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide |
| InChIKey | RXWNCPJZOCPEPQ-NVWDDTSBSA-N |
| SMILES | CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)NC(=O)[C@H](CC4=CC=C(C=C4)OC)N)O |
Computed by PubChem (NCBI)