Products 55123-66-5

CAS 55123-66-5 appears in our catalog under these names: Leupeptin hemisulfate, 95%, Leupeptin, Leupeptin hemisulphate salt monohydrate (Synthetic). Offered by: Combi-blocks, Creative Peptides, Biosynth, MedChemExpress. Available pack sizes: 100mg, on request, 25mg, 0,5mg, Get quote.

Leupeptin hemisulfate, 95%
Combi-blocks
  • size: 100mg
  • Variants: 1
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Leupeptin
Creative Peptides, Biosynth, MedChemExpress
  • size: on request, 0,5mg, Get quote
  • Variants: 3
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Leupeptin hemisulphate salt monohydrate (Synthetic)
Biosynth
  • size: 100mg, 25mg
  • Variants: 2
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Structural formula: {0} (CAS {1})

Leupeptin is a tripeptide composed of N-acetylleucyl, leucyl and argininal residues joined in sequenceby peptide linkages. It is an inhibitor of the calpains, a family of calcium-activated proteases which promote cell death. It has a role as a serine protease inhibitor, a cathepsin B inhibitor, an EC 3.4.21.4 (trypsin) inhibitor, a bacterial metabolite and a calpain inhibitor. It is an aldehyde and a tripeptide. It is a conjugate base of a leupeptin(1+).

Source: ChEBI

Identity
Molecular formulaC20H38N6O4
Molecular weight426.6 g/mol
IUPAC name(2S)-2-acetamido-N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide
InChIKeyGDBQQVLCIARPGH-ULQDDVLXSA-N
SMILESCC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O)NC(=O)C

Computed by PubChem (NCBI)

Synonyms: Leupeptin, acetyl-l-leucyl-l-leucyl-l-argininal, N-Acetyl-L-leucyl-L-leucyl-L-argininal, Ac-Leu-Leu-Arg-H, Acetyl-L-leucyl-L-leucylargininal, Leupeptin (hemisulfate), Ac-LLR-H, LEUPEPTINS [MI], BSPBio_001195, KBioGR_000535