Products 571203-78-6
CAS 571203-78-6 appears in our catalog under these names: Erastin, >95% (HPLC), Erastin/ 99.6% (existing batch purity), Erastin, Erastin, >98.0%(HPLC)(qNMR), Erastin, 98.00%. Offered by: TRC, TargetMol, GLPBio, Biosynth, TCI. Available pack sizes: 10mg, 1mg, 5mg, 500ug * 10, 1mg * 10, 1mg * 5, 50mg, 100mg.
Erastin is a member of the class of quinazolines that is quinazolin-4(3H)-one in which the hydrogens at positions 2 and 3 are replaced by 1-{4-[(4-chlorophenoxy)acetyl]piperazin-1-yl}ethyl and 2-ethoxyphenyl groups, respectively. It is an inhibitor of voltage-dependent anion-selective channels (VDAC2 and VDAC3) and a potent ferroptosis inducer. It has a role as a ferroptosis inducer, a voltage-dependent anion channel inhibitor and an antineoplastic agent. It is a tertiary carboxamide, an aromatic ether, a member of quinazolines, a diether, a N-acylpiperazine, a N-alkylpiperazine and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C30H31ClN4O4 |
|---|---|
| Molecular weight | 547.0 g/mol |
| IUPAC name | 2-[1-[4-[2-(4-chlorophenoxy)acetyl]piperazin-1-yl]ethyl]-3-(2-ethoxyphenyl)quinazolin-4-one |
| InChIKey | BKQFRNYHFIQEKN-UHFFFAOYSA-N |
| SMILES | CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl |
Computed by PubChem (NCBI)