Products 57576-44-0

CAS 57576-44-0 appears in our catalog under these names: Aclarubicin, Aclacinomycin A/ 99.43% (existing batch purity), Aclacinomycin A, Aclacinomycin A, Aclacinomycin A (Standard). Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Biosynth. Available pack sizes: on request, 10mg, 1mg, 25mg, 5mg, 2mg, Get quote, 10 mg.

Aclarubicin
Chemat Brand, TRC
  • size: on request, 10mg, 1mg, 25mg
  • Variants: 4
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Aclacinomycin A/ 99.43% (existing batch purity)
TargetMol
  • size: 1mg
  • Variants: 1
from 2086.07
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Aclacinomycin A
GLPBio
  • size: 1mg, 5mg
  • Variants: 2
from 1238.27
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Aclacinomycin A
Biosynth
  • size: 5mg, 2mg, 10mg, 25mg
  • Variants: 4
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Aclacinomycin A (Standard)
MedChemExpress
  • size: Get quote
  • Variants: 1
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Aclacinomycin A, 99.03%
MedChemExpress
  • size: 10 mg, 5 mg, 10mM/1mL, 1 mg
  • Variants: 4
from 1053.44
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Structural formula: {0} (CAS {1})

Aclacinomycin A is an anthracycline antibiotic that is produced by Streptomyces galilaeus and also has potent antineoplastic activity. It has a role as an antimicrobial agent, an antineoplastic agent, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an apoptosis inducer and a bacterial metabolite. It is a methyl ester, a polyketide, a member of phenols, an aminoglycoside, an anthracycline, a member of tetracenequinones and a trisaccharide derivative. It is functionally related to an aklavinone. It is a conjugate base of an aclacinomycin A(1+). It is a tautomer of an aclacinomycin A zwitterion.

Source: ChEBI

Identity
Molecular formulaC42H53NO15
Molecular weight811.9 g/mol
IUPAC namemethyl (1R,2R,4S)-4-[(2R,4S,5S,6S)-4-(dimethylamino)-5-[(2S,4S,5S,6S)-4-hydroxy-6-methyl-5-[(2R,6S)-6-methyl-5-oxooxan-2-yl]oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate
InChIKeyUSZYSDMBJDPRIF-SVEJIMAYSA-N
SMILESCC[C@]1(C[C@@H](C2=C(C3=C(C=C2[C@H]1C(=O)OC)C(=O)C4=C(C3=O)C(=CC=C4)O)O)O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@@H]([C@@H](O6)C)O[C@H]7CCC(=O)[C@@H](O7)C)O)N(C)C)O

Computed by PubChem (NCBI)

Synonyms: aclarubicin, Aclacinomycin A, Aclarubicine, Aclarubicinum, aclarubicina, Antibiotic MA144-A1, Aclacinomycin-A, ACM-A, Aclacur, Antibiotic MA 144A1