Products 583057-48-1

CAS 583057-48-1 appears in our catalog under these names: Arasertaconazole, (R)-Sertaconazole. Offered by: Chemat Brand, TRC, Biosynth, MedChemExpress. Available pack sizes: on request, 250mg, 50mg, 25mg, 100mg, Get quote.

Arasertaconazole
Chemat Brand, MedChemExpress
  • size: on request, Get quote
  • Variants: 2
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(R)-Sertaconazole
TRC, Biosynth
  • size: 250mg, 50mg, 25mg, 100mg
  • Variants: 4
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Structural formula: {0} (CAS {1})

Arasertaconazole is a 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}imidazole that is the active R-enantiomer of sertaconazole and is used (as its nitrate salt) for treatment of vulvovaginal candidiasis. The racemate itself is also used as a broad-spectrum antifungal drug. It has a role as a non-steroidal anti-inflammatory drug, an antibacterial drug, an antipruritic drug and an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor. It is a 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}imidazole, an imidazole antifungal drug and a conazole antifungal drug. It is a conjugate base of an arasertaconazole(1+). It is an enantiomer of a (S)-sertaconazole.

Source: ChEBI

Identity
Molecular formulaC20H15Cl3N2OS
Molecular weight437.8 g/mol
IUPAC name1-[(2R)-2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole
InChIKeyJLGKQTAYUIMGRK-IBGZPJMESA-N
SMILESC1=CC2=C(C(=C1)Cl)SC=C2CO[C@@H](CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl

Computed by PubChem (NCBI)

Synonyms: Arasertaconazole, (R)-Sertaconazole, arasertaconazol, Arasertaconazole [INN], Sertaconazole, (r)-, arasertaconazolum, orb1701182, JLGKQTAYUIMGRK-IBGZPJMESA-N
Related forms of this compound
1-[2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole C20H15Cl3N2OS