Products 59721-28-7
CAS 59721-28-7 appears in our catalog under these names: Camostat free base, Camostat, 99.42%, Camostat, 99%. Offered by: TargetMol, MedChemExpress, Chemat. Available pack sizes: 25mg, 50mg, 100mg, 100 mg, 25 mg, 10mM/1mL, 10 mg, 5 mg.
Camostat is a benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients. It has a role as an anticoronaviral agent, an antiviral agent, an antineoplastic agent, an antihypertensive agent, an antifibrinolytic drug, a serine protease inhibitor and an anti-inflammatory agent. It is a tertiary carboxamide, a member of guanidines, a carboxylic ester, a benzoate ester and a diester. It is functionally related to a 4-guanidinobenzoic acid. It is a conjugate base of a camostat(1+).
Source: ChEBI
| Molecular formula | C20H22N4O5 |
|---|---|
| Molecular weight | 398.4 g/mol |
| IUPAC name | [4-[2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl]phenyl] 4-(diaminomethylideneamino)benzoate |
| InChIKey | XASIMHXSUQUHLV-UHFFFAOYSA-N |
| SMILES | CN(C)C(=O)COC(=O)CC1=CC=C(C=C1)OC(=O)C2=CC=C(C=C2)N=C(N)N |
Computed by PubChem (NCBI)
Synonyms:
Camostat, camostate, Camostatum, 4-{2-[(dimethylcarbamoyl)methoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate, 4-(2-((dimethylcarbamoyl)methoxy)-2-oxoethyl)phenyl 4-carbamimidamidobenzoate, Camostat [INN], Camostat (INN), 4-(2-(2-(Dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl 4-guanidinobenzoate, Camostatum [INN-Latin], camostat-mesilate