Products 599150-20-6

CAS 599150-20-6 appears in our catalog under these names: 2-Methoxyethyl 4-(3-hydroxyphenyl)-7-(2-methoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate, 95%, GLI antagonist-1, 95+%, HPI 1/ 94.4% (existing batch purity), HPI 1, 4-(3-Hydroxyphenyl)-1-(2-Methoxyethyl)-7-(2-Methoxyphenyl)-2-Methyl-4,6,7,8-Tetrahydroquinolin-5(1H)-One, ≥98%, ≥98%. Offered by: Combi-blocks, AmBeed, TargetMol, GLPBio, Chemat. Available pack sizes: 250mg, 1g, 5g, 1mg, 2mg, 5mg, 10mg, 25mg.

2-Methoxyethyl 4-(3-hydroxyphenyl)-7-(2-methoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate, 95%
Combi-blocks
  • size: 250mg, 1g
  • Variants: 2
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GLI antagonist-1, 95+%
AmBeed
  • size: 5g, 1g
  • Variants: 2
from 7855.96
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HPI 1/ 94.4% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 8
from 445.96
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HPI 1
GLPBio
  • size: 1mg, 5mg
  • Variants: 2
from 625.12
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4-(3-Hydroxyphenyl)-1-(2-Methoxyethyl)-7-(2-Methoxyphenyl)-2-Methyl-4,6,7,8-Tetrahydroquinolin-5(1H)-One, ≥98%, ≥98%
Chemat
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 5
from 626.00
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Hh Pathway-IN-1, 99.06%
MedChemExpress
  • size: 1 mg, 25 mg, 50 mg, 100 mg
  • Variants: 6
from 361.49
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Structural formula: {0} (CAS {1})

HPI-1 is a quinolone that is 4,6,7,8-tetrahydroquinolin-5(1H)-one substituted by methyl, (2-methoxyethoxy)carbonyl, 3-hydroxyphenyl, and 2-methoxyphenyl groups at positions 2, 3, 4, and 7, respectively. It is a Hedgehog signaling pathway inhibitor. It has a role as a Hedgehog signaling pathway inhibitor and an antineoplastic agent. It is a quinolone, a monomethoxybenzene, an ether, a member of phenols and an enoate ester.

Source: ChEBI

Identity
Molecular formulaC27H29NO6
Molecular weight463.5 g/mol
IUPAC name2-methoxyethyl 4-(3-hydroxyphenyl)-7-(2-methoxyphenyl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxylate
InChIKeyZXSWZQSYZYMZKS-UHFFFAOYSA-N
SMILESCC1=C(C(C2=C(N1)CC(CC2=O)C3=CC=CC=C3OC)C4=CC(=CC=C4)O)C(=O)OCCOC

Computed by PubChem (NCBI)

Synonyms: GLI antagonist-1, ZXSWZQSYZYMZKS-UHFFFAOYSA-N, Hh Signaling Antagonist XII, Hedgehog Pathway Inhibitor 1, Hedgehog Pathway Inhibitor-1