Products 59973-80-7

CAS 59973-80-7 appears in our catalog under these names: Sulindac EP Impurity B (Sulindac USP Related Compound B, Sulindac Sulfone), (Z)-(5-Fluoro-2-methyl-1-(4-(methylsulfonyl)benzylidene)-1H-inden-3-yl)acetic Acid (Sulindac Sulfone), Sulindac EP Impurity B, (Z)-Sulindac Sulfone, >95% (HPLC), Exisulind/ 98.08% (existing batch purity). Offered by: Chemat Brand, Mikromol, TRC, TargetMol, Biosynth. Available pack sizes: on request, 4x25mg, 25mg, 100mg, 10mg, 5mg, 50mg, 2mg.

Sulindac EP Impurity B (Sulindac USP Related Compound B, Sulindac Sulfone)
Chemat Brand
  • size: on request
  • Variants: 1
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(Z)-(5-Fluoro-2-methyl-1-(4-(methylsulfonyl)benzylidene)-1H-inden-3-yl)acetic Acid (Sulindac Sulfone)
Mikromol
  • size: 4x25mg
  • Variants: 1
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Sulindac EP Impurity B
Mikromol
  • size: 25mg
  • Variants: 1
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(Z)-Sulindac Sulfone, >95% (HPLC)
TRC
  • size: 100mg, 10mg, 25mg
  • Variants: 3
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Exisulind/ 98.08% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 5
from 492.36
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Sulindac sulfone
Biosynth
  • size: 5mg, 2mg, 10mg, 25mg
  • Variants: 5
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Sulindac sulfone 97%
Ambeed
  • size: 1mg, 50mg, 100mg, 250mg
  • Variants: 5
from 153.44
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Sulindac sulfone, 97%, 97%
Chemat
  • size: 1mg, 50mg, 100mg, 250mg
  • Variants: 5
from 98.00
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Sulindac sulfone, 98.10%
MedChemExpress
  • size: 10 mg, 1 mg, 5 mg
  • Variants: 3
from 361.49
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Structural formula: {0} (CAS {1})

Sulindac sulfone is a sulfone metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. It inhibits the development and induces regression of premalignant adenomatous polyps. Lipoxygenase and Cox-2 inhibitor. It has a role as a cyclooxygenase 2 inhibitor, an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor and an apoptosis inducer. It is a monocarboxylic acid, a sulfone and an organofluorine compound. It is functionally related to a sulindac.

Source: ChEBI

Identity
Molecular formulaC20H17FO4S
Molecular weight372.4 g/mol
IUPAC name2-[(3Z)-6-fluoro-2-methyl-3-[(4-methylsulfonylphenyl)methylidene]inden-1-yl]acetic acid
InChIKeyMVGSNCBCUWPVDA-MFOYZWKCSA-N
SMILESCC\1=C(C2=C(/C1=C\C3=CC=C(C=C3)S(=O)(=O)C)C=CC(=C2)F)CC(=O)O

Computed by PubChem (NCBI)

Synonyms: Sulindac sulfone, Exisulind, Prevatec, cis-5-Fluoro-2-methyl-1-(p-methylsulfonylbenzylidenyl)indene-3-acetic acid, 5-Fluoro-2-methyl-1-((Z)-p-(methylsulfonyl)benzylidene)indene-3-acetic acid, exisulindum, Aptosyn, Exisulind [INN], (Z)-Sulindac Sulfone, SULINDAC SULPHONE
Related forms of this compound
2-[(3E)-6-fluoro-2-methyl-3-[(4-methylsulfonylphenyl)methylidene]inden-1-yl]acetic acid C20H17FO4S
2-[(3Z)-6-fluoro-2-methyl-3-[[4-(trideuteriomethylsulfonyl)phenyl]methylidene]inden-1-yl]acetic acid C20H17FO4S