CAS 606143-52-6 appears in our catalog under these names: Selumetinib, >95% (HPLC), Selumetinib/ 99.46% (existing batch purity), AZD6244(Selumetinib), Selumetinib, Selumetinib, >95.0%(HPLC)(T). Offered by: TRC, TargetMol, GLPBio, Chemat, Biosynth. Available pack sizes: 100mg, 10mg, 1g, 25mg, 50mg, 200mg, 500mg, 10mM (in 1ml dmso).
Selumetinib is a member of the class of benzimidazoles that is 1-methyl-1H-benzimidazole which is substituted at positions 4, 5, and 6 by fluorine, (4-bromo-2-chlorophenyl)amino, and N-(2-hydroxyethoxy)aminocarbonyl groups, respectively. It is a MEK1 and MEK2 inhibitor. It has a role as an anticoronaviral agent, an antineoplastic agent and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is a member of benzimidazoles, an organofluorine compound, a member of bromobenzenes, a secondary amino compound, a hydroxamic acid ester and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C17H15BrClFN4O3 |
|---|---|
| Molecular weight | 457.7 g/mol |
| IUPAC name | 6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide |
| InChIKey | CYOHGALHFOKKQC-UHFFFAOYSA-N |
| SMILES | CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO |
Computed by PubChem (NCBI)