Products 608141-41-9

CAS 608141-41-9 appears in our catalog under these names: Apremilast, Apremilast, >95% (HPLC), Apremilast/ 99.21% (existing batch purity), Apremilast (CC–10004), Apremilast - Bio-X â„¢. Offered by: Chemat Brand, TRC, Mikromol, TargetMol, GLPBio. Available pack sizes: on request, 100mg, 2,5g, 5mg, 250mg, 10mg, 25mg, 200mg.

Apremilast
Chemat Brand, Mikromol, Biosynth
  • size: on request, 250mg, 10g, 5g
  • Variants: 10
from 572.00
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Apremilast, >95% (HPLC)
TRC
  • size: 100mg, 2,5g, 5mg
  • Variants: 3
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Apremilast/ 99.21% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 100mg
  • Variants: 6
from 465.53
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Apremilast (CC–10004)
GLPBio
  • size: 10mg, 25mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 5
from 648.53
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Apremilast - Bio-X â„¢
Biosynth
  • size: 10mg
  • Variants: 1
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Apremilast, >98.0%(HPLC)(T)
TCI
  • size: 5g
  • Variants: 1
from 1421.42
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Apremilast, 99.87%
MedChemExpress
  • size: 5 mg, 25 mg, 100 mg, 500 mg
  • Variants: 8
from 384.71
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Apremilast (Standard)
MedChemExpress
  • size: 25 mg, 5 mg, 100 mg, 50 mg
  • Variants: 5
from 649.42
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Apremilast, BioScience Grade, 10 mg
Roth
  • size: 10mg
  • Variants: 1
from 514.44
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Apremilast, 98%
Ambeed, Fluorochem
  • size: 1g, 5g, 25g
  • Variants: 5
from 232.23
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(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, 98%
BLDpharm, Chemat
  • size: 1g, 5g, 25g, 1mg
  • Variants: 12
from 83.60
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Structural formula: {0} (CAS {1})

Apremilast is a member of the class of isoindoles that is isoindole-1,3-dione substituted at position 4 by an acetamido group and at position 1 by a 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl group. Used for treatment of psoriatic arthritis. It has a role as a non-steroidal anti-inflammatory drug and a phosphodiesterase IV inhibitor. It is a N-acetylarylamine, an aromatic ether, a sulfone and a member of phthalimides.

Source: ChEBI

Identity
Molecular formulaC22H24N2O7S
Molecular weight460.5 g/mol
IUPAC nameN-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide
InChIKeyIMOZEMNVLZVGJZ-QGZVFWFLSA-N
SMILESCCOC1=C(C=CC(=C1)[C@@H](CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC

Computed by PubChem (NCBI)

Synonyms: Apremilast, OTEZLA, apremilastum, Apremilast (CC-10004), Apremilast [USAN], APREMILAST [INN], APREMILAST [VANDF], Apremilast [USAN:INN], Apremilast?, (S)-Apremilast
Related forms of this compound
N-[2-[(1R)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide C22H24N2O7S
N-[2-[(1S)-1-[4-methoxy-3-(1,1,2,2,2-pentadeuterioethoxy)phenyl]-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide C22H24N2O7S
N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide C22H24N2O7S
N-[2-[1-[4-methoxy-3-(1,1,2,2,2-pentadeuterioethoxy)phenyl]-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide C22H24N2O7S
Isomers (same molecular formula)
N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-5-yl]acetamide C22H24N2O7S
N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-5-yl]acetamide C22H24N2O7S
N-[2-[1-(4-ethoxy-3-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide C22H24N2O7S