Products 67452-97-5

CAS 67452-97-5 appears in our catalog under these names: Alclometasone, 7alpha-Chloro-16alpha-methyl Prednisolone. Offered by: Hubei YoungXin, TRC, MedChemExpress. Available pack sizes: 10mg, 25mg, 50mg, 100mg, 200mg, Get quote.

Alclometasone
Hubei YoungXin, MedChemExpress
  • size: 10mg, 25mg, 50mg, 100mg
  • Variants: 6
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7alpha-Chloro-16alpha-methyl Prednisolone
TRC
  • size: 100mg
  • Variants: 1
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Structural formula: {0} (CAS {1})

Alclometasone is a prednisolone compound having an alpha-chloro substituent at the 7-position and an alpha-methyl substituent at the 16-position. It has a role as an anti-inflammatory drug and an antipruritic drug. It is a primary alpha-hydroxy ketone, a tertiary alpha-hydroxy ketone, a glucocorticoid, a 17alpha-hydroxy steroid, a 21-hydroxy steroid, an 11beta-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a chlorinated steroid. It is functionally related to a prednisolone.

Source: ChEBI

Identity
Molecular formulaC22H29ClO5
Molecular weight408.9 g/mol
IUPAC name(7R,8S,9S,10R,11S,13S,14S,16R,17R)-7-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
InChIKeyFJXOGVLKCZQRDN-PHCHRAKRSA-N
SMILESC[C@@H]1C[C@H]2[C@@H]3[C@@H](CC4=CC(=O)C=C[C@@]4([C@H]3[C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)C)Cl

Computed by PubChem (NCBI)

Synonyms: alclometasone, Aclometasone, 7alpha-Chloro-16alpha-methylprednisolone, alclometasonum, alclometasona, Alclometasone [INN:BAN], Alclometasone (INN), ALCLOMETASONE [INN], 7?-Chloro-16?-methyl Prednisolone, ALCLOMETASONE [MI]
Isomers (same molecular formula)
(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-4,6,6-trideuterio-17-(2,2-dideuterio-2-hydroxyacetyl)-11,17-dihydroxy-10,13,16-trimethyl-8,11,12,14,15,16-hexahydro-7H-cyclopenta[a]phenanthren-3-one C22H29ClO5
(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one C22H29ClO5
(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one C22H29ClO5