Products 698387-09-6

CAS 698387-09-6 appears in our catalog under these names: Neratinib, Neratinib/ 96.17% (existing batch purity), Neratinib (HKI–272), Neratinib, >95.0%(HPLC)(T), Neratinib, 98.00%. Offered by: Chemat Brand, TRC, TargetMol, GLPBio, TCI. Available pack sizes: on request, 100mg, 10mg, 5mg, 25mg, 50mg, 200mg, 500mg.

Neratinib
Chemat Brand, TRC, Biosynth
  • size: on request, 100mg, 10mg, 5mg
  • Variants: 12
from 449.90
View product
Neratinib/ 96.17% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 386.15
View product
Neratinib (HKI–272)
GLPBio
  • size: 100mg, 25mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 4
from 568.96
View product
Neratinib, >95.0%(HPLC)(T)
TCI
  • size: 100mg
  • Variants: 1
from 1106.71
View product
Neratinib, 98.00%
Chemat
  • size: 10mg, 5mg
  • Variants: 2
from 339.13
View product
Neratinib - Bio-X â„¢
Biosynth
  • size: 1mg
  • Variants: 1
View product
Neratinib 98%
Ambeed
  • size: 1mg, 5mg, 10mg, 10g
  • Variants: 8
from 175.69
View product
(2E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide, 98%, 98%
Chemat
  • size: 1mg, 5mg, 10mg, 100mg
  • Variants: 8
from 78.80
View product
Neratinib, 99.94%
MedChemExpress
  • size: 200 mg, 10 mg, 50 mg, 10mM/1mL
  • Variants: 6
from 384.71
View product
Neratinib (Standard), 99.25%
MedChemExpress
  • size: 25 mg, 5 mg, 10 mg, 100 mg
  • Variants: 5
from 454.37
View product
Neratinib, 99%
Fluorochem
  • size: 100mg, 250mg, 1g
  • Variants: 3
from 294.71
View product
Structural formula: {0} (CAS {1})

Neratinib is a quinoline compound having a cyano group at the 3-position, a 3-chloro-4-(2-pyridylmethoxy)anilino group at the 4-position, a 4-dimethylamino-trans-but-2-enoylamido group at the 6-position, and an ethoxy group at the 7-position. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It is a nitrile and a member of quinolines.

Source: ChEBI

Identity
Molecular formulaC30H29ClN6O3
Molecular weight557.0 g/mol
IUPAC name(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
InChIKeyJWNPDZNEKVCWMY-VQHVLOKHSA-N
SMILESCCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C

Computed by PubChem (NCBI)

Synonyms: Neratinib, neratinibum, Neratinib (HKI-272), Nerlynx, C30H29ClN6O3, Neratinib [USAN], Neratinib [USAN:INN], 698387-09-6 (free base), Neratinib (Standard), NERATINIB [INN]
Related forms of this compound
(E)-4-[bis(trideuteriomethyl)amino]-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]but-2-enamide C30H29ClN6O3
(Z)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide C30H29ClN6O3