Products 70209-81-3

CAS 70209-81-3 appears in our catalog under these names: Ivermectin B1b, Ivermectin B1b, 22,23-Dihydroavermectin B1b (Ivermectin B1b), Ivermectin B1b, 98.66%, Ivermectin. Offered by: Chemat Brand, Hubei YoungXin, TRC, TargetMol, GLPBio. Available pack sizes: on request, 10mg, 25mg, 50mg, 100mg, 200mg, 1mg, 2,5mg.

Ivermectin B1b
Chemat Brand, Hubei YoungXin, TRC
  • size: on request, 10mg, 25mg, 50mg
  • Variants: 10
from 5107.46
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Ivermectin B1b
GLPBio
  • size: 2,5mg, 500μg
  • Variants: 2
from 2338.19
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22,23-Dihydroavermectin B1b (Ivermectin B1b)
Biosynth
  • size: 2mg, 1mg, 5mg, 10mg
  • Variants: 4
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Ivermectin B1b, 98.66%
MedChemExpress
  • size: 5 mg, 500 μg, 1 mg, 10 mg
  • Variants: 4
from 1438.90
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Ivermectin
Chemat Brand
  • size: on request
  • Variants: 1
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Structural formula: {0} (CAS {1})

22,23-dihydroavermectin B1b is a macrocyclic lactone that is avermectin B1b in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the minor component of ivermectin. It is a macrocyclic lactone and a spiroketal. It is functionally related to an avermectin B1b.

Source: ChEBI

Identity
Molecular formulaC47H72O14
Molecular weight861.1 g/mol
IUPAC name(1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethyl-6'-propan-2-ylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
InChIKeyVARHUCVRRNANBD-PVVXTEPVSA-N
SMILESC[C@H]1CC[C@]2(C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)O[C@@H]1C(C)C

Computed by PubChem (NCBI)

Synonyms: Ivermectin B1b, Avermectin H2B1b, Ivermectin Component B1b, dihydroavermectin B1b, 22,23-dihydroavermectin B1b, Stromectol (TN), Soolantra (TN), Sklice (TN), H2B1b, Ivermectin (JAN/USP/INN)
Isomers (same molecular formula)
(1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-12-[(2R,4S,5S,6S)-5-[(2S,4S,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-21,24-dihydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one C47H72O14
(1R,4S,5'S,6S,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5R,6S)-4-hydroxy-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one C47H72O14