Products 722543-31-9

CAS 722543-31-9 appears in our catalog under these names: 5-[[7-[3-[ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-3-acetamide, 95%, Barasertib, AZD1152, Barasertib/ 99.63% (existing batch purity), AZD 1152. Offered by: Combi-blocks, TRC, GLPBio, TargetMol, Biosynth. Available pack sizes: 100mg, 500mg, 250mg, 10mg, 400mg, 5mg, 10mM (in 1ml dmso), 50mg.

5-[[7-[3-[ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-3-acetamide, 95%
Combi-blocks
  • size: 100mg, 500mg
  • Variants: 2
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Barasertib
TRC
  • size: 250mg
  • Variants: 1
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AZD1152
GLPBio
  • size: 10mg, 400mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 6
from 704.69
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Barasertib/ 99.63% (existing batch purity)
TargetMol
  • size: 2mg, 5mg, 10mg, 25mg
  • Variants: 5
from 458.82
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AZD 1152
Biosynth
  • size: 5mg, 2mg
  • Variants: 2
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Barasertib 98%
Ambeed
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 5
from 392.62
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2-(Ethyl(3-((4-((3-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-5-yl)amino)quinazolin-7-yl)oxy)propyl)amino)ethyl dihydrogen phosphate, 98%, 98%
Chemat
  • size: 5mg
  • Variants: 1
from 371.60
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Barasertib, 99.50%
MedChemExpress
  • size: 100 mg, 50 mg, 10mM/1mL, 5 mg
  • Variants: 6
from 528.67
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Barasertib (Standard)
MedChemExpress
  • size: Get quote
  • Variants: 1
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Structural formula: {0} (CAS {1})

AZT-1152 is a dihydrogen phosphate prodrug of a pyrazoloquinazoline aurora kinase inhibitor AZD1152-hydroxyquinazoline pyrazol anilide(HQPA) and is converted rapidly to the active AZD1152-HQPA in plasma. It has a role as an antineoplastic agent, a prodrug and an Aurora kinase inhibitor. It is an anilide, a secondary carboxamide, a monoalkyl phosphate, a member of pyrazoles, a member of quinazolines, a secondary amino compound, a tertiary amino compound and a member of monofluorobenzenes. It is functionally related to an AZD-1152.

Source: ChEBI

Identity
Molecular formulaC26H31FN7O6P
Molecular weight587.5 g/mol
IUPAC name2-[ethyl-[3-[4-[[5-[2-(3-fluoroanilino)-2-oxoethyl]-1H-pyrazol-3-yl]amino]quinazolin-7-yl]oxypropyl]amino]ethyl dihydrogen phosphate
InChIKeyGBJVVSCPOBPEIT-UHFFFAOYSA-N
SMILESCCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCOP(=O)(O)O

Computed by PubChem (NCBI)

Synonyms: Barasertib, barasertibum, Aurora Kinase Inhibitor AZD1152, Barasertib [INN], Barasertib (who-dd), BARASERTIB [WHO-DD], Kinome_3324, Azd1152 trifluoroacetic acid, Barasertib, >98% (HPLC), orb1707614