Products 732302-99-7

CAS 732302-99-7 appears in our catalog under these names: Givinostat hydrochloride monohydrate/ 98.09% (existing batch purity), ITF2357 (Givinostat), Givinostat hydrochloride hydrate, Givinostat HCl monohydrate 98%, Givinostat (hydrochloride monohydrate), 99.63%. Offered by: TargetMol, GLPBio, Biosynth, Ambeed, MedChemExpress. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 500mg, 1g, 200mg.

Givinostat hydrochloride monohydrate/ 98.09% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 651.67
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ITF2357 (Givinostat)
GLPBio
  • size: 10mg, 1g, 200mg, 5mg
  • Variants: 7
from 802.98
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Givinostat hydrochloride hydrate
Biosynth
  • size: 250mg, 500mg
  • Variants: 2
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Givinostat HCl monohydrate 98%
Ambeed
  • size: 5mg, 50mg, 100mg, 250mg
  • Variants: 5
from 409.31
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Givinostat (hydrochloride monohydrate), 99.63%
MedChemExpress
  • size: 50 mg, 10mM/1mL, 100 mg, 25 mg
  • Variants: 6
from 551.89
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Givinostat (hydrochloride monohydrate) (Standard)
MedChemExpress
  • size: 50 mg, 25 mg, 5 mg, 10 mg
  • Variants: 5
from 1150.97
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(6-((Diethylamino)methyl)naphthalen-2-yl)methyl (4-(hydroxycarbamoyl)phenyl)carbamate hydrochloride hydrate, 98%, 98%
Chemat
  • size: 5mg, 50mg, 100mg, 250mg
  • Variants: 4
from 232.40
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Structural formula: {0} (CAS {1})

Givinostat hydrochloride monohydrate is the monohydrate form of givinostat hydrochloride. It is a histone deacetylase inhibitor indicated for the treatment of Duchenne muscular dystrophy in patients 6 years of age and older. It has a role as an antineoplastic agent, an angiogenesis inhibitor, an EC 3.5.1.98 (histone deacetylase) inhibitor, an anti-inflammatory agent and an apoptosis inducer. It contains a givinostat hydrochloride.

Source: ChEBI

Identity
Molecular formulaC24H30ClN3O5
Molecular weight476.0 g/mol
IUPAC name[6-(diethylaminomethyl)naphthalen-2-yl]methyl N-[4-(hydroxycarbamoyl)phenyl]carbamate;hydrate;hydrochloride
InChIKeyFKGKZBBDJSKCIS-UHFFFAOYSA-N
SMILESCCN(CC)CC1=CC2=C(C=C1)C=C(C=C2)COC(=O)NC3=CC=C(C=C3)C(=O)NO.O.Cl

Computed by PubChem (NCBI)

Synonyms: Givinostat Hydrochloride Hydrate, Givinostat hydrochloride monohydrate, Givinostat (ITF2357), Givinostat (hydrochloride monohydrate), Givinostat hydrochloride (USAN), GIVINOSTAT HYDROCHLORIDE [USAN], Duvyzat (TN), 2,4-bis(chloranyl), Givinostat HCl monohydrate, Givinostat (ITF2357)?