Products 748142-15-6
CAS 748142-15-6 appears in our catalog under these names: SGC–CLK–1, SGC-CLK-1, 99.12%, Sgc-clk-1 25 Mg, Sgc-clk-1 5 Mg. Offered by: GLPBio, MedChemExpress, Sigma-Aldrich. Available pack sizes: 1mg, 10mg, 5mg, 10mM/1mL, 10 mg, 50 mg, 25 mg, 5 mg.
SGC-CLK-1 is a pyrazolopyridazine that is pyrazolo[1,5-b]pyridazine which is substituted by a 2-[3-methoxy-5-(trifluoromethyl)anilino]pyrimidin-4-yl group at position 3 and by a methoxy group at position 6. It is a human GSK-3beta, CDK2, CDK4, CLK1, CLK2, and CLK4 kinase inhibitor. It has a role as an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor, an EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor and an EC 2.7.11.26 (tau-protein kinase) inhibitor. It is a monomethoxybenzene, an aromatic ether, a member of pyrimidines, a pyrazolopyridazine, a substituted aniline, a secondary amino compound and a member of (trifluoromethyl)benzenes.
Source: ChEBI
| Molecular formula | C19H15F3N6O2 |
|---|---|
| Molecular weight | 416.4 g/mol |
| IUPAC name | 4-(6-methoxypyrazolo[1,5-b]pyridazin-3-yl)-N-[3-methoxy-5-(trifluoromethyl)phenyl]pyrimidin-2-amine |
| InChIKey | GJYVLTPTDBQQCY-UHFFFAOYSA-N |
| SMILES | COC1=NN2C(=C(C=N2)C3=NC(=NC=C3)NC4=CC(=CC(=C4)C(F)(F)F)OC)C=C1 |
Computed by PubChem (NCBI)