CAS 781661-94-7 appears in our catalog under these names: YM155 (Sepantronium Bromide), YM155, >95% (HPLC), Sepantronium bromide/ 99.82% (existing batch purity), YM155, Sepantronium bromide 98%. Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Biosynth. Available pack sizes: on request, 10mg, 25mg, 2mg, 5mg, 50mg, 100mg, 500mg.
Sepantronium bromide is an organic bromide salt consisting of sepantronium cations and bromide anions. It has been found to selectively inhibit survivin (BIRC5) gene promoter activity and to down-regulate survivin in vitro, so leading to induction of apoptosis. It has a role as a survivin suppressant, an antineoplastic agent and an apoptosis inducer. It contains a sepantronium.
Source: ChEBI
| Molecular formula | C20H19BrN4O3 |
|---|---|
| Molecular weight | 443.3 g/mol |
| IUPAC name | 1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione bromide |
| InChIKey | QBIYUDDJPRGKNJ-UHFFFAOYSA-M |
| SMILES | CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-] |
Computed by PubChem (NCBI)