CAS 83647-97-6 appears in our catalog under these names: (S)-7-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid, 98+%, Spirapril. Offered by: Chemat Brand, MedChemExpress. Available pack sizes: on request, Get quote.
Spirapril is an azaspiro compound resulting from the formal condensation of the amino group of (8S)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid with the carboxy group of N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanine. It is a prodrug for the antihypertensive drug spiraprilat. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, an antihypertensive agent and a prodrug. It is a tertiary carboxamide, an ethyl ester, an azaspiro compound, a dicarboxylic acid monoester, a dipeptide, a pyrrolidinecarboxylic acid, a secondary amino compound and a dithioketal. It is functionally related to a spiraprilat.
Source: ChEBI
| Molecular formula | C22H30N2O5S2 |
|---|---|
| Molecular weight | 466.6 g/mol |
| IUPAC name | (8S)-7-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid |
| InChIKey | HRWCVUIFMSZDJS-SZMVWBNQSA-N |
| SMILES | CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3(C[C@H]2C(=O)O)SCCS3 |
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