Products 854601-70-0

CAS 854601-70-0 appears in our catalog under these names: Naloxegol, Naloxegol (NKTR-118), Naloxegol (NKTR–118), Naloxegol-d7 Oxalate. Offered by: Chemat Brand, TRC, TargetMol, GLPBio, MedChemExpress. Available pack sizes: on request, 10mg, 1mg, 5mg, 25mg, 50mg, 100mg, Get quote.

Naloxegol
Chemat Brand, TRC, MedChemExpress
  • size: on request, 10mg, 1mg, 5mg
  • Variants: 5
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Naloxegol (NKTR-118)
TargetMol
  • size: 25mg, 50mg, 100mg
  • Variants: 3
from 10732.68
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Naloxegol (NKTR–118)
GLPBio
  • size: 10mg, 100mg, 5mg, 50mg
  • Variants: 4
from 1916.94
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Naloxegol-d7 Oxalate
Chemat Brand
  • size: on request
  • Variants: 1
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Structural formula: {0} (CAS {1})

Naloxegol is an organic heteropentacyclic compound that is naloxone in which the keto group is replaced by a PEG moiety. Used for treatment of opioid-induced constipation. It has a role as a mu-opioid receptor antagonist and a cathartic. It is a tertiary alcohol, a member of phenols, an aromatic ether, an organic heteropentacyclic compound and a polyether. It is functionally related to a naloxone. It derives from a hydride of a morphinan.

Source: ChEBI

Identity
Molecular formulaC34H53NO11
Molecular weight651.8 g/mol
IUPAC name(4R,4aS,7S,7aR,12bS)-7-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
InChIKeyXNKCCCKFOQNXKV-ZRSCBOBOSA-N
SMILESCOCCOCCOCCOCCOCCOCCOCCO[C@H]1CC[C@]2([C@H]3CC4=C5[C@]2([C@H]1OC5=C(C=C4)O)CCN3CC=C)O

Computed by PubChem (NCBI)

Synonyms: Naloxegol, moventig, naloxegolum, Movantik, Naloxone Impurity 20, Naloxegol [INN], Naloxegol [USAN:INN], NALOXEGOL [MI], Naloxegol (USAN/INN), NALOXEGOL [USAN]