Products 855527-92-3

CAS 855527-92-3 appears in our catalog under these names: NBI-74330, 99.76%, (R)-N-(1-(3-(4-Ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-(pyridin-3-ylmethyl)acetamide, 98%, 98%, NBI-74330 98%. Offered by: MedChemExpress, Chemat, Ambeed. Available pack sizes: 10mM/1mL, 50 mg, 100 mg, 25 mg, 10 mg, 1mg, 5mg, 5 mg.

Structural formula: {0} (CAS {1})

NBI-74330 is a potent antagonist for CXCR3, and exhibits potent inhibition of (125I)CXCL10 and (125I)CXCL11 specific binding with Ki of 1.5 and 3.2 nM, respectively.

Source: ChEBI

Identity
Molecular formulaC32H27F4N5O3
Molecular weight605.6 g/mol
IUPAC nameN-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide
InChIKeyXMRGQUDUVGRCBS-HXUWFJFHSA-N
SMILESCCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2[C@@H](C)N(CC4=CN=CC=C4)C(=O)CC5=CC(=C(C=C5)F)C(F)(F)F

Computed by PubChem (NCBI)