Products 876310-60-0
CAS 876310-60-0 appears in our catalog under these names: RF9, RF 9, RF9 trifluoroacetate salt, RF9, 99.37%, N2-(Tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)-L-arginyl-L-phenylalaninamide, 95%. Offered by: TargetMol, GLPBio, Biosynth, MedChemExpress, Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 5 mg, 1 mg.
RF9 is a dipeptide formed from L-arginine and L-phenylalaninamide residues in which a hydrogen attached to the nitrogen of the alpha-amino group of the arginine residue has been replaced by a 1-adamantanecarbonyl group. It has been reported to be a potent and selective antagonist of neuropeptide FF (NPFF) receptors, but more recently found to be an agonist at both NPFF1R and the kisspeptin receptor (KISS1R). It has a role as a neuropeptide FF receptor antagonist, a neuropeptide FF receptor agonist and a kisspeptin receptor agonist. It is functionally related to an Arg-Ala.
Source: ChEBI
| Molecular formula | C26H38N6O3 |
|---|---|
| Molecular weight | 482.6 g/mol |
| IUPAC name | N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]adamantane-1-carboxamide |
| InChIKey | UMKHUSRDQFQHAK-RNJMTYCLSA-N |
| SMILES | C1C2CC3CC1CC(C2)(C3)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N |
Computed by PubChem (NCBI)
Synonyms:
1-adamantanecarbonyl-Arg-Phe-NH2, N2-(Tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)-L-arginyl-L-phenylalaninamide, 1-Adamantanecarbonyl-RF-NH2, orb1706724, N(2)-(tricyclo[3.3.1.1(3,7)]decan-1-ylcarbonyl)-L-arginyl-L-phenylalaninamide, N~2~-(Tricyclo[3.3.1.1~3,7~]decane-1-carbonyl)-L-arginyl-L-phenylalaninamide