Products 876755-27-0

CAS 876755-27-0 appears in our catalog under these names: (2S,3S)-2-((R)-4-(4-(2-Hydroxyethoxy)phenyl)-2,5-dioxo-imidazolidin-1-yl)-3-phenyl-N-(4-propionylthiazol-2-yl)butyramide, RO 4927350. Offered by: Biosynth, MedChemExpress. Available pack sizes: 25mg, 1mg, 5mg, 10mg, 50mg, Get quote.

(2S,3S)-2-((R)-4-(4-(2-Hydroxyethoxy)phenyl)-2,5-dioxo-imidazolidin-1-yl)-3-phenyl-N-(4-propionylthiazol-2-yl)butyramide
Biosynth
  • size: 25mg, 1mg, 5mg, 10mg
  • Variants: 5
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RO 4927350
MedChemExpress
  • size: Get quote
  • Variants: 1
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Structural formula: {0} (CAS {1})

RO4927350 is a carboxamide resulting from the formal condensation of the primary amino group of 4-propanoyl-1,3-thiazol-2-amine with the carboxy group of a 3-phenylbutiyric acid which has been substituted at position 2 by a (4R)-4-[p-(2-hydroxyethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl group. It is a potent, highly selective inhibitormitogen-activated protein kinase 1/2 inhibitor. It has a role as an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is a secondary carboxamide, an imidazolidine-2,4-dione, a member of 1,3-thiazoles and an aromatic ketone.

Source: ChEBI

Identity
Molecular formulaC27H28N4O6S
Molecular weight536.6 g/mol
IUPAC name(2S,3S)-2-[(4R)-4-[4-(2-hydroxyethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]-3-phenyl-N-(4-propanoyl-1,3-thiazol-2-yl)butanamide
InChIKeyRKKBPPTYPGTSEA-FNVCAUGXSA-N
SMILESCCC(=O)C1=CSC(=N1)NC(=O)[C@H]([C@@H](C)C2=CC=CC=C2)N3C(=O)[C@H](NC3=O)C4=CC=C(C=C4)OCCO

Computed by PubChem (NCBI)

Synonyms: Ro 4927350, RKKBPPTYPGTSEA-FNVCAUGXSA-N, orb1741021