Products 908027-21-4
CAS 908027-21-4 is the registry number for MI 63. Offered by: MedChemExpress. Available pack sizes: Get quote.
MI-63 is an azaspiro compound resulting from the formal fusion of position 3 of 6-chloro-oxindole with position 3 of (2R,3SS5S)-3-(3-chloro-2-fluorophenyl)-5-(2,2-dimethylpropyl)-N-[2-(morpholin-4-yl)ethyl]pyrrolidine-2-carboxamide. It is a potent inhibitor of the MDM2-p53 interaction. It has a role as an apoptosis inducer. It is a secondary carboxamide, an azaspiro compound, a member of pyrrolidines, a member of oxindoles, a member of morpholines, a member of monochlorobenzenes and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C29H35Cl2FN4O3 |
|---|---|
| Molecular weight | 577.5 g/mol |
| IUPAC name | (2'R,3S,3'S,5'R)-6-chloro-3'-(3-chloro-2-fluorophenyl)-5'-(2,2-dimethylpropyl)-N-(2-morpholin-4-ylethyl)-2-oxospiro[1H-indole-3,4'-pyrrolidine]-2'-carboxamide |
| InChIKey | YTBYOWZWBDYLQF-BGLPIVGWSA-N |
| SMILES | CC(C)(C)C[C@@H]1[C@]2([C@H]([C@@H](N1)C(=O)NCCN3CCOCC3)C4=C(C(=CC=C4)Cl)F)C5=C(C=C(C=C5)Cl)NC2=O |
Computed by PubChem (NCBI)
Synonyms:
orb1741085