Products 918504-65-1
CAS 918504-65-1 appears in our catalog under these names: Vemurafenib, Vemurafenib, >95% (HPLC), Vemurafenib/ 99.65% (existing batch purity), Vemurafenib (PLX4032, RG7204), PLX4032. Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Chemat. Available pack sizes: on request, 10mg, 25mg, 5mg, 50mg, 100mg, 200mg, 500mg.
Vemurafenib is a pyrrolopyridine that is 1H-pyrrolo[2,3-b]pyridine which is substituted at position 5 by a p-chlorophenyl group and at positions 3 by a 3-amino-2,6-difluorobenzoyl group, the amino group of which has undergone formal condensation with propane-1-sulfonic acid to give the corresponding sulfonamide. An inhibitor of BRAF and other kinases. It has a role as an antineoplastic agent and a B-Raf inhibitor. It is a sulfonamide, a difluorobenzene, a pyrrolopyridine, an aromatic ketone and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C23H18ClF2N3O3S |
|---|---|
| Molecular weight | 489.9 g/mol |
| IUPAC name | N-[3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]propane-1-sulfonamide |
| InChIKey | GPXBXXGIAQBQNI-UHFFFAOYSA-N |
| SMILES | CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)Cl)F |
Computed by PubChem (NCBI)