Products 936727-05-8

CAS 936727-05-8 appears in our catalog under these names: Lumacaftor (VX-809), VX 809, >95% (HPLC), Lumacaftor/ 99.72% (existing batch purity), VX–809, Lumacaftor. Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Biosynth. Available pack sizes: on request, 10mg, 50mg, 5mg, 25mg, 100mg, 500mg, 10mM (in 1ml dmso).

Lumacaftor (VX-809)
Chemat Brand
  • size: on request
  • Variants: 1
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VX 809, >95% (HPLC)
TRC
  • size: 10mg, 50mg, 5mg
  • Variants: 3
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Lumacaftor/ 99.72% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 465.53
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VX–809
GLPBio
  • size: 10mg, 5mg, 10mM (in 1ml dmso), 50mg
  • Variants: 4
from 760.86
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Lumacaftor
Biosynth
  • size: 250mg, 100mg, 500mg, 1000mg
  • Variants: 5
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Lumacaftor 98%
Ambeed
  • size: 1mg, 5mg, 100mg, 250mg
  • Variants: 7
from 120.06
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3-(6-{[1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarbonyl]-amino}-3-methyl-pyridin-2-yl)-benzoicacid, 98%, 98%
Chemat
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 5
from 184.40
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Lumacaftor, 99.85%
MedChemExpress
  • size: 10 mg, 50 mg, 5 mg, 100 mg
  • Variants: 6
from 384.71
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Lumacaftor (Standard)
MedChemExpress
  • size: 100 mg, 5 mg, 50 mg, 25 mg
  • Variants: 5
from 886.26
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Lumacaftor-d4 (VX-809-d4)
Chemat Brand
  • size: on request
  • Variants: 1
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Lumacaftor-d4 (VX-809-d4)
Hubei YoungXin
  • size: 10mg, 25mg, 50mg, 100mg
  • Variants: 5
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Structural formula: {0} (CAS {1})

Lumacaftor is an aromatic amide obtained by formal condensation of the carboxy group of 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid with the aromatic amino group of 3-(6-amino-3-methylpyridin-2-yl)benzoic acid. Used for the treatment of cystic fibrosis. It has a role as a CFTR potentiator and an orphan drug. It is a member of benzoic acids, a member of pyridines, an organofluorine compound, a member of benzodioxoles, a member of cyclopropanes and an aromatic amide.

Source: ChEBI

Identity
Molecular formulaC24H18F2N2O5
Molecular weight452.4 g/mol
IUPAC name3-[6-[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl]amino]-3-methyl-2-pyridinyl]benzoic acid
InChIKeyUFSKUSARDNFIRC-UHFFFAOYSA-N
SMILESCC1=C(N=C(C=C1)NC(=O)C2(CC2)C3=CC4=C(C=C3)OC(O4)(F)F)C5=CC(=CC=C5)C(=O)O

Computed by PubChem (NCBI)

Synonyms: Lumacaftor, ORKAMBI COMPONENT LUMACAFTOR, lumacaftorum, Lumacaftor(vx-809vx809), Lumacaftor (USAN), LUMACAFTOR [USAN], Lumacaftor [INN], Lumacaftor [USAN:INN], LUMACAFTOR [MI], Lumacaftor (USAN/INN)