Products 946128-88-7

CAS 946128-88-7 appears in our catalog under these names: RO5126766(CH5126766), Ro 5126766/ 98.3% (existing batch purity), Ro 5126766, Avutometinib 98%, 3-[[2-[(Methylaminosulfonyl)amino]-3-fluoropyridin-4-yl]methyl]-4-methyl-7-[(pyrimidin-2-yl)oxy]-2H-1-benzopyran-2-one, 98%, 98%. Offered by: GLPBio, TargetMol, Biosynth, Ambeed, Chemat. Available pack sizes: 10mg, 25mg, 5mg, 1mg, 2mg, 50mg, 100mg, 250mg.

RO5126766(CH5126766)
GLPBio
  • size: 10mg, 25mg, 5mg
  • Variants: 3
from 868.51
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Ro 5126766/ 98.3% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 7
from 525.34
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Ro 5126766
Biosynth
  • size: 5mg, 2mg, 10mg, 25mg
  • Variants: 4
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Avutometinib 98%
Ambeed
  • size: 250mg, 1mg, 5mg, 10mg
  • Variants: 7
from 359.25
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3-[[2-[(Methylaminosulfonyl)amino]-3-fluoropyridin-4-yl]methyl]-4-methyl-7-[(pyrimidin-2-yl)oxy]-2H-1-benzopyran-2-one, 98%, 98%
Chemat
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 7
from 165.20
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Avutometinib, 99.43%
MedChemExpress
  • size: 10 mg, 5 mg, 10mM/1mL, 50 mg
  • Variants: 5
from 858.40
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CH5126766 is a member of the class of coumarins that is 4-methyl-7-[(pyrimidin-2-yl)oxy]coumarin carrying an additional [2-[(methylaminosulfonyl)amino]-3-fluoropyridin-4-yl]methyl substituent at position 3. It has a role as an antineoplastic agent and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is a member of coumarins, a member of pyridines, an organofluorine compound, an aryloxypyrimidine and a member of sulfamides.

Source: ChEBI

Identity
Molecular formulaC21H18FN5O5S
Molecular weight471.5 g/mol
IUPAC name3-[[3-fluoro-2-(methylsulfamoylamino)-4-pyridinyl]methyl]-4-methyl-7-pyrimidin-2-yloxychromen-2-one
InChIKeyLMMJFBMMJUMSJS-UHFFFAOYSA-N
SMILESCC1=C(C(=O)OC2=C1C=CC(=C2)OC3=NC=CC=N3)CC4=C(C(=NC=C4)NS(=O)(=O)NC)F

Computed by PubChem (NCBI)

Synonyms: avutometinib, Raf/MEK Inhibitor VS-6766, Ro 5126766, Ro 5126766 - Bio-X, 3wig, CHU, Avutometinib [WHO-DD], Avutometinib (USAN/INN), AVUTOMETINIB [INN], AVUTOMETINIB [USAN]