Products 95399-71-6
CAS 95399-71-6 appears in our catalog under these names: Fosinopril EP Impurity A (Fosinopril USP Related Compound A, Fosinoprilat), Fosinopril EP Impurity A, Fosinoprilat, >95% (HPLC), Fosfenopril, 98%, (4S)-4-Cyclohexyl-((4-phenylbutyl)phosphinyl)acetyl-L-proline. Offered by: Chemat Brand, TRC, AmBeed, Mikromol, GLPBio. Available pack sizes: on request, 50mg, 5mg, 10mg, 25mg, 100mg, 10 mg, 25 mg.
Fosinoprilat is a phosphinic acid-containing N-acyl derivative of (4S)-cyclohexyl-L-proline. An inhibitor of angiotensin converting enzyme (ACE), it is used as the phosphinate ester pro-drug fosinopril for treatment of hypertension and chronic heart failure. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and an antihypertensive agent. It is a member of phosphinic acids and a L-proline derivative.
Source: ChEBI
| Molecular formula | C23H34NO5P |
|---|---|
| Molecular weight | 435.5 g/mol |
| IUPAC name | (2S,4S)-4-cyclohexyl-1-[2-[hydroxy(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid |
| InChIKey | WOIWWYDXDVSWAZ-RTWAWAEBSA-N |
| SMILES | C1CCC(CC1)[C@@H]2C[C@H](N(C2)C(=O)CP(=O)(CCCCC3=CC=CC=C3)O)C(=O)O |
Computed by PubChem (NCBI)
Synonyms:
Fosinoprilat, fosfenopril, Fosinopril diacid, Fosinoprilic acid, Fosinoprilatum, (4S)-4-Cyclohexyl-1-((hydroxy(4-phenylbutyl)phosphinyl)acetyl)-L-proline, L-Proline, 4-cyclohexyl-1-((hydroxy(4-phenylbutyl)phosphinyl)acetyl)-, trans-, (4S)-4-cyclohexyl-1-{[hydroxy(4-phenylbutyl)phosphoryl]acetyl}-L-proline, (4S)-4-cyclohexyl-1-((hydroxy(4-phenylbutyl)phosphoryl)acetyl)-L-proline, L-Proline, 4-cyclohexyl-1-[[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-,(4S)-